2025 AHA科学声明：饮酒与心血管疾病.pdfVIP

Circulation

AHASCIENTIFICSTATEMENT

AlcoholUseandCardiovascularDisease:

AScientificStatementFromtheAmerican

HeartAssociation

MariannR.Piano,RN,PhD,FAHA,Chair;GregoryM.Marcus,MD,FAHA,ViceChair;DawnM.Aycock,PhD,RN,FAHA;

JenniferBuckman,PhD;Chueh-LungHwang,PhD,PT;SusannaC.Larsson,PhD;KennethJ.Mukamal,MD,MPH,FAHA;

MichaelRoerecke,PhD;onbehalftheAmericanHeartAssociationCouncilonLifestyleandCardiometabolicHealth;Councilon

CardiovascularandStrokeNursing;CouncilonClinicalCardiology;andStrokeCouncil

ABSTRACT:Alcoholisoneofthemostcommonlyconsumedsubstancesintheworld,exhibitingcomplexrelationshipswith

multipleaspectsofcardiovascularhealthanddisease.Themajorityoftheresearchonthetopicisobservationalandtherefore

pronetobiasandconfounding.Theavailableevidencesuggestsnorisktopossibleriskreductionwhenalcoholisconsumed

inlowamounts(suchasnomorethan1to2drinksaday)inregardtocoronaryarterydisease,stroke,suddendeath,and

possiblyheartfailure.Theriskassociatedwithconsuming1to2drinksadayonatrialfibrillationremainsunknown.More

randomizedtrialsoflowtomoderatealcoholconsumptionareneededformoredefinitiveconclusions.Instarkcontrast,

heavieralcoholconsumptionsuchasbingedrinkingorconsumingonaverage≥3drinks/disconsistentlyassociatedwith

worseoutcomesineverycardiovasculardiseaseentitystudied.Consideringthelevelofevidence,itremainsunknown

whetherdrinkingispartofahealthylifestyleandthereforecliniciansshouldreinforcehealthylifestylebehaviorssuchas

regularlyengaginginphysicalactivity,avoidingtobaccouse,andmaintaininghealthybodyweight.

KeyWords:AHAScientificStatements◼alcoholconsumption◼atrialfibrillation◼cardiovasculardiseases◼coronaryarterydisease

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