2025 AHA科学声明：S ARS-CoV2 急性后后遗 症（长 COVID）患者运动不耐受及对训练的反应.pdfVIP

Circulation

AHASCIENTIFICSTATEMENT

ExerciseIntoleranceandResponsetoTraining

inPatientsWithPostacuteSequelaeofSARS-

CoV2(LongCOVID):AScientificStatement

FromtheAmericanHeartAssociation

WilliamK.CornwellIII,MD,MSCS,Chair;BenjaminD.Levine,MD,FAHA,ViceChair;DianeBaptiste,DNP;

NicoleBhave,MD,FAHA;SarikaDesai,MD;ElizabethDineen,DO;MatthewDurstenfeld,MD,MAS;JustinEdward,MD;

MuHuang,PhD,DPT;RoniJacobsen,MD;JonathanH.Kim,MD,FAHA;EricaSpatz,MD;onbehalfoftheAmericanHeart

AssociationExercise,CardiacRehabilitation,andSecondaryPreventionCommitteeoftheCouncilonClinicalCardiology;Council

onCardiovascularandStrokeNursing;CouncilonHypertension;CouncilonLifestyleandCardiometabolicHealth;Councilon

PeripheralVascularDisease;andStrokeCouncil

ABSTRACT:ThepostacutesequelaeofSARS-CoV-2,alsoknownasLongCOVID,mayaffect10%to25%ofindividuals

diagnosedwithSARS-CoV-2.Morethan100symptomshavebeenreportedamongpatientswithLongCOVID,but

almostallpatientsreportseverefatigue,orthostaticintolerance,shortnessofbreath,andreductionsinexercisetolerance.

Emergingdatasuggestthatcardiovasculardeconditioningplaysamajorroleinthedevelopmentofthissyndromeandthat

reductionsinfunctionalcapacityamongpatientswithLongCOVIDarecomparabletoreductionsseenamongindividuals

withcardiovasculardeconditioningresultingfrombedrest.Concernhasbeenraisedabouttheuseofexercisetraining

aspartofthemanagementstrategyforpatientswithLongCOVID.However,exercisetrainingappropriatelytailoredto

thepatientwithcardiovasculardeconditioningmaybeaneffectivestrategytofacilitateimprovementinsymptoms.This

AmericanHeartAssociationscientificstatementprovidesaconciseyetcomprehensiveoverviewofmechanismscontributing

todevelopmentof