2-Decanone-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

2-Decanone

Cat.No.:HY-W010203

CASNo.:693-54-9

分⼦式:C₁₀H₂₀O

分⼦量:156.27

作⽤靶点:Fungal

作⽤通路:Anti-infection

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性2-Decanone是⼀种抗真菌剂。2-Decanone能够抑制病原体的菌丝⽣长、孢⼦萌发以及芽管的形成。2-

Decanone会下调与孢⼦萌发相关的基因MfBmp1以及侵染结构形成基因MfPls1,促使活性氧物质ROS的积

累,从⽽引发线粒体损伤以及随后的孢⼦凋亡。2-Decanone有望⽤于果蔬采后病害防控的研究。

IC50TargetHumanEndogenousMetabolite

REFERENCES

[1].HibiM,etal.Attempttosimultaneouslygeneratethreechiralcentersin4-hydroxyisoleucinewithmicrobialcarbonylreductases.Bioorg

MedChem.2018Apr1;26(7):1327-1332.

[2].WangX,etal.Antifungalactivityof2-decanoneagainstMoniliniafructicolaanditsapplicationincombinationwithboscalidinmitigating

brownrotdiseaseinpeachfruit[J].PhysiologicalandMolecularPlantPathology,2025,138:102665.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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