6R-8S-10R-11S-13S-14R-17-2-Acetoxyacetyl-11-hydroxy-6-10-13-trimethyl-3-oxo-6-7-8-9-10-11-12-13-14-15-16-17-dodecahydro-3H-cyclopenta-a-phenanthren-17-yl-propionate-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

(6R,8S,10R,11S,13S,14R)-17-(2-Acetoxyacetyl)-11-hydroxy-6,10,13-

trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-

cyclopenta[a]phenanthren-17-ylpropionate

Cat.No.:HY-W711915

CASNo.:91898-32-7

分⼦式:C₁₄H₃₂O₂Si

分⼦量:260.49

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(6R,8S,10R,11S,13S,14R)-17-(2-Acetoxyacetyl)-11-hydroxy-6,10,13-trimethyl-3-oxo-

6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-ylpropionate是⼀种

PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE23ubiquitinligaseand

theotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.