6-Chlorohexanoic-acid-epsilon-Chlorocaproic-acid-生命科学试剂-MCE.pdfVIP

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6-Chlorohexanoicacid

Cat.No.:HY-W017416

CASNo.:4224-62-8

Synonyms:epsilon-Chlorocaproicacid

分⼦式:C₆H₁₁ClO₂

分⼦量:150.6

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature3years

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature3years)

BIOLOGICALACTIVITY

⽣物活性6-Chlorohexanoicacid(epsilon-Chlorocaproicacid)是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE439ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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