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6-Methoxyflavone(Standard)

Cat.No.:HY-W097625R

CASNo.:26964-24-9

分⼦式:C₁₆H₁₂O₃

分⼦量:252.27

作⽤靶点:Toll-likeReceptor(TLR);MyD88;p38MAPK;NF-κB;

ReferenceStandards;HemeOxygenase(HO);PERK

作⽤通路:Immunology/Inflammation;MAPK/ERKPathway;NF-κB;

Others;MetabolicEnzyme/Protease;CellCycle/DNADamage

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性6-Methoxyflavone(Standard)是6-Methoxyflavone(HY-W097625)的分析标准品。本产品⽤于研究及分析应

⽤。6-Methoxyflavone是⼀种具有⼝服活性的甲氧基黄酮。6-Methoxyflavone通过抑制TLR4/MyD88/p38

MAPK/NF-κB依赖途径和激活HO-1/NQO-1信号通路，抑制⼩胶质细胞中的神经炎症。6-Methoxyflavone通

过CCNA2/CDK2/p21CIP1

REFERENCES

[1].ZhangC,QuanY,YangL,BaiY,YangY.6-MethoxyflavoneinducesS-phasearrestthroughtheCCNA2/CDK2/p21CIP1signaling

pathwayinHeLacells.Bioengineered.2022Mar;13(3):7277-7292.

[2].ArifM,RaufK,RehmanNU,TokhiA,IkramM,SewellRD.6-MethoxyflavoneandDonepezilBehavioralPlusNeurochemicalCorrelates

inReversingChronicEthanolandWithdrawalInducedCognitiveImpairment.DrugDesDevelTher.2022May28;16:1573-1593.

[3].ChenWF,etal.6-methoxyflavonesuppressesneuroinflammationinlipopolysaccharide-stimulatedmicr