养心通脉饮治疗冠心病稳定型心绞痛（气虚痰瘀证）的临床观察及对血管内皮糖萼的影响.docxVIP

养心通脉饮治疗冠心病稳定型心绞痛（气虚痰瘀证）的临床观察及对血管内皮糖萼的影响

【摘要】

本研究旨在探讨养心通脉饮在治疗冠心病稳定型心绞痛（气虚痰瘀证）中的疗效及其对血管内皮糖萼的影响。通过随机对照试验，选取符合纳入标准的冠心病稳定型心绞痛患者60例，随机分为对照组和实验组，每组30例。对照组给予常规西药治疗，实验组在此基础上加用养心通脉饮。疗程为4周。主要观察指标包括临床症状、心电图变化、血液生化指标以及血管内皮糖萼的变化。结果显示，实验组患者在治疗后心绞痛发作次数明显减少，心电图改善情况显著优于对照组，血液生化指标也有所改善。同时，实验组患者的血管内皮糖萼水平较治疗前显著降低，说明养心通脉饮能够有效改善冠心病稳定型心绞痛患者的临床症状，并可能通过调节血管内皮糖萼水平发挥治疗效果。

【关键词】

冠心病；稳定型心绞痛；气虚痰瘀证；养心通脉饮；血管内皮糖萼

【Abstract】

ThisstudyaimstoexplorethetherapeuticeffectofYangxinTongmaiYinonstableanginapectorisincoronaryheartdisease(QideficiencyandPhlegm-stasissyndrome)anditsimpactonvascularendothelialglycocalyx.Arandomizedcontrolledtrialwasconducted,selecting60patientswithstableanginapectorisincoronaryheartdiseasewhomettheinclusioncriteria,randomlydividedintocontrolgroupandexperimentalgroup,eachconsistingof30cases.ThecontrolgroupreceivedconventionalWesternmedicinetreatment,whiletheexperimentalgroupaddedYangxinTongmaiYin.Thetreatmentperiodwas4weeks.Themainobservationindicatorsincludedclinicalsymptoms,electrocardiogramchanges,bloodbiochemicalindicators,andchangesinvascularendothelialglycocalyx.Theresultsshowedthattheexperimentalgrouphadasignificantreductioninthefrequencyofanginapectorisattacksaftertreatment,andtheelectrocardiogramimprovedsignificantlycomparedtothecontrolgroup.Bloodbiochemicalindicatorsalsoimproved.Atthesametime,thelevelofvascularendothelialglycocalyxintheexperimentalgroupwassignificantlylowerthanbeforetreatment,indicatingthatYangxinTongmaiYincaneffectivelyimprovetheclinicalsymptomsofpatientswithstableanginapectorisincoronaryheartdisease,andmayplayatherapeuticeffectthroughregulatingthelevelofvascularendothelialglycocalyx.

【Keywords】

Coronaryheartdisease;Stableanginapectoris;QideficiencyandPhlegm-stasissyndrome;YangxinTongmaiYin;Vascularendothelialglycocalyx【Abstract】

本研究旨在探讨养心通脉饮在治