急性肾炎课件.ppt

AcuteNephritis

急性肾炎Post-infectiousglomerulonephritisPost-streptococcalglomerulonephritis

AcuteNephritischaracterizedby:Fluidretention(Edema,Hypertension)HematuriaOliguriaGroupA?-hemolyticstreptococci(historyofinfection,positiveculture/elevatedantistreptolysintitle)

grosshematuria（肉眼血尿）microscopichematuria（镜下血尿）Cinicalfeatures均一性/非均一性

Pathology

NormalglomerulusAGNPathology

PathologyWithinfiltrationbyhematogenouscells,mostnotablyPMNS

PathologyInAGN,immunofluorescentstudiesshowfinelygranularstainingforIgGinperipheralcapillaryloopsandinmesang