自自噬通路化合物筛选库（96孔板格式）.xlsxVIP

Index Plate Row Col Volume（microliter） Concentration（mM） ID MOLENAME Synonyms CAS SMILES Formula MolWt Pathways Target Receptor Bioactivity Reference

1 M41670 A 2 50 10 T2245 CL387785 CL387785;CL-387785;WAY-EKI785;EKI-785 194423-06-8 CC#CC(=O)Nc1cc2c(cc1)ncnc2Nc1cc(ccc1)Br C18H13BrN4O 381.23 Angiogenesis;JAK/STATsignaling;TyrosineKinase/Adaptors EGFRinhibitor EGFR CL-387785(EKI785;WAY-EKI785)isanirreversibleinhibitorofEGFR（IC50：370+/-120pM）;isabletoovercomeresistancecausedbytheT790Mmutationonafunctionallevel. DiscafaniCM,etal.BiochemPharmacol.1999,57(8),9