抗病毒治疗副作用及处理.pptVIP

**抗病毒治疗副作用及处理MajorTargetsofAntiretroviralAgentsHIVRNADNAdsDNARTIntegraseTranscriptionProviralDNASplicedmRNAmRNAGenomicRNAPolyproteinProteaseProteaseInhibitorsSQV,RTV,IDV,NFV,LPV/r,ATV,fAPV,TPV,DRVRTInhibitorsNRTI:AZT,d4T,ddI,3TC,FTC,ABCNNRTI:NVP,EFV,ETV,RPVNTRTI:Tenofovir123456EntryInhibitorsCCR4:AMD3100,T22CCR5:Maraviroc,SCH-CFusiongp41:EnfuvirtidevprIntegraseinhibitorsRaltegravirSmithC,CROI2009;145D.A.D研究：33,347患者2.192死亡病例（共158,959人.年)13.8例死亡/1,000人.年