英语Chapter 10 Regulatory Strategies.pdfVIP

C H A P T E R 10 Regulatory Strategies Like motor traffic, metabolic pathways flow more efficiently when regulated by signals. Cytidine triphosphate (CTP), the final product of a multistep pathway, controls flux through the pathway by inhibiting the committed step catalyzed by aspartate transcarbamoylase (ATCase). [(Left) Michael Winokur Photography/ Getty Images.] The activity of enzymes must often be regulated so that they function at O U T L I N E the proper time and place. This regulation is essential for coordination of the vast array of biochemical processes taking place at any instant in an 10.1 Aspartate Transcarbamoylase Is organism. Enzymatic activity is regulated in five principal ways: Allosterically Inhibited by the End Product of Its Pathway 1. Allosteric Control. Allosteric proteins contain distinct regulatory sites 10.2 Isozymes Provide a Means of and multiple functional sites. The binding of small signal molecules at regu- Regulation Specific to Distinct latory sites is a significant means of controlling the activity of these proteins. Tissues and Developmental Moreover, allosteric proteins show the propert