病理学英文课件_6.1EpithelialTumor_.pptVIP

Section 8 Epithelial Tumor 1. Benign epithelial tumors (1) Papilloma Origin: coverage epithelium Shape: finger-like projections into the lumen or on the surface of skin Site: commonly in skin or bladder. (2) Adenoma Origin: adenocytes Type ① Typical adenoma ② Cystadenoma: having single or multiple cysts containing watery secretion. Commonly in ovary ③ Fibroademoma: both adenocytes and fibrous are parenchymal compositions. commonly in breast ④ Plesmorphic adenoma: having gland, mucoid, and cartilage-like tissues. Commonly in salivary gland. ⑤ Polypous adenoma: single or multiple. commonly in gastrointestinal track. 2. Malignant epithehal tumors (1) Squamous cell carcinoma Origin: squamous cell Morphology: grossly: cauliflower-like, polyp, mushroom-like, ulceration. Histological: Well-differentiated type are similar to normal squamous epithelial cells, with intercellular bridges and nets of keratin pearls (carcinoma pearls). But poor-differentiated type are pleomorphism, no intercellular bridges and keratin pearls. (2) Basal cell carcinoma Origin: basal cells of skin Features: locally invasive growth, almost never metastasis commonly in face of oldster. (3) Transitional cell carcinoma Origin: transitional cells Features: exoteric, finger-like, commonly in bladder, renal pelvis. (4) Adenocarcinoma Origin: adenocytes large quantities of type: ① Typical adenocarcinoma ② Mucoid carcinoma or colloid Signet-ring cell and carcinoma mucin ③ Solid carcinoma or carcinoma simplex Poor differentiation adenoma carcinoma, and the tumor cells arrange in solid columns, or masses. Type: a. Sclerous carcinoma: dense stroma b. Medullary carcinoma encephaloid carcinoma: Little stroma, and large masses of tumor cells. c. Carcinoma simplex: Poor differentiation adenocarcinoma with equal quantities of tumor cells and stroma. 3. Premalignant diseases dysplasia, and carcinoma in situ. (1)