Advances in Human Assisted Reproductive Technology-汕医《妇产科学》课件.pptVIP

Advances in Human Assisted Reproductive Technology Xu Lan The Dept. of G O, the First Affiliated Hospital of Shantou University Medical College Infertility is a frequent medical problem around the world Infertility affects about 15% of all couples attempting pregnancy Human Assisted Reproductive Techniques Artificial Insemination In vitro Fertilization-Embryo Transfer(IVF-ET) Intracytoplasmic Sperm Injection(ICSI) Pre-implantation Genetic Diagnosis(PGD) Artificial Insemination Definition：Place sperm into female reproductive tract by artificial method, but not sexual intercourse AIH (Artificial Insemination by Husband) 夫精人工受精, 1790 AID (Artificial Insemination by Donor) 供精人工授精, 1884 Artificial Insemination Indications Abnormal Semen Parameters Cervical Factors Abnormal Post-coital Test Difficulties in Sexual Intercourse Artificial Insemination Semen preparation Swim-up separation Percoll continuous gradient separation Wang’s Tubal separation Double-washing separation Artificial Insemination Artificial Insemination Features of Artificial Insemination Only involving in semen samples preparation in vitro There is no changes for the process of fertilization of sperm and oocyte compared with normal pregnancy The pregnancy rate is about 20% Easy, economic In Vitro Fertilization and Embryo Transfer IVF－ET Who needs IVF-ET It is effective to overcome a variety of infertility problems, particularly tubal or marked sperm deficiencies. Tubal problems Immunologic infertility Ovulatory problems(oocyte donor) Sperm problems Uterus dysformation(surrogate) Other problems In Vitro Fertilization Embryo Transfer Embryo Transfer Demands for embryo transfer Condition：the development of endometrium should be coordinated simutaneously with that of embryo Corpus lutem support In Vitro Fertilization Embryo Transfer Significance： _Get rid of the traditional mode of marriage-sex-fertility, making it possible to control the process of human reproduction in vitro _p