免疫学英文版课件_Immunodeficiencytalk_.pptVIP

* Immunodeficiency: B Cell Development First described in 1952 by Dr Ogden Bruton -Brutons Agammaglobulinemia -Congenital Agammaglobulinemia Inherited immunodeficiency male disease in which patients lack the ability to produce -Antibodies -Proteins that make up gamma globulin -Immunoglobulin fraction of blood plasma Affected males Few or no B cells and lymph nodes are very small No tonsils and cervical lymph nodes Serum Usually no IgA, IgM, IgD, or IgE; small amounts of IgG from placenta First 6-12 months Protection by maternal IgG from placenta to fetus As IgG is exhausted Males develop re