免疫学英文版课件_mcsharrymastcells_mast_cells_in_lung_tissue_.pptVIP

mast cells in lung tissue basophil Basophil and Mast cell : introduction bone marrow derived granulocytes myeloid lineage Paul Ehrlich 1879 deep violet blue metachromatic acidic mambrane-bound granules basophils usually less than 0.2% of WBC secretory function mast cell : function distributed in organs which interface with exterior: lung, nasal tissue, skin, gut. sentinel or surveillance function increase (mast cell hyperplasia) associated with parasite infections allergy mastocytoma (rare) increase in blood precursors - basophils Mast cell : IL-3, 4 and SCF (c-KitL) Mast cell recruitment, pro