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AJCC分期的时刻课件.pptVIP

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AJCC Staging Moments AJCC TNM Staging 7th Edition Colon Case #1 Colon Case # 1 Presentation of New Case Newly diagnosed colon cancer patient Presentation at Cancer Conference for treatment recommendations and clinical staging Colon Case # 1 History Physical 51 yr old female who presented with an abnormal screening colonoscopy Family history of colon ca Colon Case # 1 Imaging Endoscopy Results Colonoscopy-1.5cm pedunculated polyp at 60cm in transverse colon CT abd/pelvis-negative Colon Case # 1 Diagnostic Procedure Procedure Polypectomy, transverse colon at 60cm Pathology Report Adenocarcinoma Grade 2-3 Invasion into lamina propria Stalk margins widely free, clear by 4mm Colon Case # 1 Clinical Staging Clinical staging Uses information from the physical exam, imaging, and diagnostic biopsy Purpose Select appropriate treatment Estimate prognosis Colon Case # 1 Clinical Staging Synopsis- patient with 1.5cm pedunculated polyp resected on screening colonoscopy, nodes negative on imaging What is the clinical stage? T____ N____ M____ Stage Group______ Colon Case # 1 Clinical Staging Clinical Stage correct answer pTis cN0 cM0 Stage Group 0 Based on stage, treatment is selected Review NCCN treatment guidelines for this stage Colon Case # 1 Clinical Staging Rationale for staging choices pTis Invasion of lamina propria Pathologic since the stalk margin was clear cN0 because nodes were clinically negative on imaging cM0 because there was nothing to suggest distant metastases; if there was, appropriate tests would be performed before developing a treatment plan Prognostic Factors Clinically Significant Applicable to this case Pre-op or Pre-Rx CEA: not done There are no prognostic factors required for staging Colon Case # 1 Presentation after Surgery Patient had polypectomy during their screening colonoscopy This patient was recommended for observation only, no further treatment Colon Case # 1 Pathologic Staging Pathologic staging Uses informati

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