自动化与精益生产在欧美及印度的发展.pdfVIP

自动化与精益生产 在欧美及印度的发展 The Trend of Automation and Lean Manufacture India and Europe 内容Content  设计发展概况 Trends and Facility Design Aspects  固体处理中的问题 Things that go wrong in Solids Handling 精益固体加工 Lean Solids Handling 工厂设计中的最新考量因素Trends that have an impact on facility design:  灵活性Flexibility - 快速更换产品Quick changeover ( 仿制类药品 Generics)  减少清洗Reduce cleaning – 密闭生产工艺closed processes  缩减成本Reduce Cost – 精益Lean - 平衡流动Balancing Flow / 减少 等待reduce waiting/库存Inventory  稳定的工艺Robust processes – 需要稳定、可靠的物料处理require robust/reliable materials handling 精益固体处理需求 Lean Solids Handling Requirements 出现的问题Things that go wrong 架桥与结块Bridging and Blocking 物料挤压或粘结在一起在出口上部形成桥状Materials interlock or bond together to build a stable bridge above outlet. (同时会出现物料倾泻和料仓需剧烈震动occurs with ‘’Flood Feed’’ and excessive vibration of the container) 精益固体处理需求 Lean Solids Handling Requirements 出现的问题Things that go wrong _ 在下料过程中需要通风以平衡、 置换下游工艺中排挤出的空气 通风Venting 或氮气，避免产生的负压影响 物料流动和称量精度 Is required during discharge to vent/balance displaced air/N² from the down line process to the feed vessel, to avoid adverse + over/under pressure which affects flow and weighing accuracy. 精益固体处理需求 Lean Solids Handling Requirements 出现的问题Things that go wrong 分层Segregation / De-mixing 导致因素caused by: 1. CORE/FUNNEL FLOW 中心下料  桶壁摩擦导致仅中心下料Wall friction causes flow through