大脑组织分层体网格建立及变形技术研究.pdfVIP

2011;31(10) 南方医科大学学报（J South Med Univ ） ·1675 · ·基础研究· 大脑组织分层体网格建立及变形技术研究 陈春晓，王 睿，彭娴璐，吴佳妮 南京航空航天大学生物医学工程系，江苏 南京 210016 摘要：虚拟手术系统在辅助医生合理制定术前方案以提高手术成功率方面有重要意义。虚拟手术系统主要由医学数据 可视化与建模和人体组织器官(主要是软组织)受力形变仿真两部分构成。针对大脑的复杂结构，本文采用混合水平集并 结合阈值分割及形态学方法，可有效地将大脑磁共振图像分割成头部轮廓、灰质、白质、脑脊液和脑室五部分，并利用课题 组开发的基于约束的Delaunay 算法及iso2mesh 等开源工具包，建立了脑组织的四面体网格，并对各部分组织对应的网格 分别进行标记。最后利用得到的具有真实解剖结构的有限元网格，对软组织的形变进行了研究，建立了基于Tensor- Mass 模型的点触和球触变形模拟。本文的研究可进一步提高大脑虚拟手术的定位精度和反映大脑组织形变的过程。 关键词：图像分割；体网格；Delaunay ；软组织形变；Tensor-Mass 中图分类号：O436 文献标志码：A 文章编号：1673-4254（2011）10-1675-07 Segmental meshing of brain tissues and simulation of soft tissue deformation CHEN Chun-xiao, WANG Rui, PENG Xian-lu, WU Jia-ni Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China Abstract: Virtual surgery provides important assistance in preoperative planning of brain surgeries. A virtual surgery system essentially consists of visualization and modeling of the medical data and deformation simulation of human organs (mainly soft tissues). We used the hybrid level set theory, threshold segmentation, and morphological methods to segment the human head MRI volumetric data into five parts, namely the outline of the head, gray matter, white matter, cerebrospinal fluid and ventricles. The iso2mesh toolkit based on Delaunay algorithm was then employed to generate the tetrahedral mesh and mark the five parts. We further studied the soft tissue deformation, and established a mechanic model based on Tensor-Mass system to simulate the point-touch and ball-touch models for soft tissue deformation. This approach can help to improve the positioning accuracy of a virtual brain surgery