生理学_邹原_留学生Chapter4Cardiovascularphysiology.pptVIP

Chapter 4 Cardiovascular system The heart Electrical and mechanical activities The vascular system Blood pressure Regulation of the cardiovascular system Anatomy of the heart Section 1 Bioelectricity of the heart RP and AP Non-automatic cell: working cell Automatic cell: Sinoatrial node (SAN), AV node, Purkinje cell Working cell Resting Potential: -90mv, an equilibrium potential of K+. Ik1 channel Action potential: Phase 0,1,2,3,4 Ventricular Action potential Phase 0: Upstroke –90mv to +20-30mv Duration: 1-2 ms Max. Velocity: 200-400 v/s Fast sodium channel Fast response cell Blocker is