Vol5No2Feb2011基于T2信噪比的低场磁共振系统T2.pdfVIP

Vol. 5 No.2/ Feb. 2011 基于T信噪比的低场磁共振系统T测量 2 2 T Mapping in Low Field MR 2 Systems Based on T2 NR 戴睿彬 吴垠 潘艳丽 谢国喜 刘新 摘 要 针对低场磁共振系统信噪比低的特点，研究能提高低场磁共振系统T 定量测量准确性的优化曲线拟合方法。 目的 2 方法 采用多回波自旋回波序列扫描获得T 加权图像，利用对各体元处T 的估值，自适应的优化用于相应的体元进行曲线拟合所用的回 2 2 波数，由此达到优化T 信噪比的目的，实现了一种基于T 信噪比优化的自适应曲线拟合算法。用现有的截断型曲线拟合方法作为对 2 2 比，分别通过数值仿真、体模及人体实验对新算法的改进效果进行评估。结果 与截断型拟合方法相比，所提出的自适应拟合方法 可得到信噪比更高、测量结果更准确的T 定量图谱。结论 曲线拟合方法会影响T 测量的准确性，基于T 信噪比优化的自适应曲线拟 2 2 2 合算法能提高T2测量的准确性。 关键词 磁共振成像；T 图谱；T 信噪比；曲线拟合 2 2 ABSTRACT　Objective Considering the characteristics of low SNR in low field MR systems, an optimized curve fitting method was studied, with which accuracy of quantitative T2 mapping will be improved in low field MR systems. Methods Series of T2-weighted images were acquired using a multi-echo spin echo sequence. According to certain voxel wised T estimation, T NR optimization was achieved via optimizing the number of echoes used for curve fitting in the 2 2 corresponding voxel. Thus, an adaptive curve fitting method based on T NR optimization for T mapping was performed. 2 2 As a comparison, truncated curve fitting method was implemented. Evaluation was performed with both methods via numerical simulation, phantom study and in vivo study respectively. Result