成人女性寰椎朗格汉斯细胞增多症一例及文献复习.pdfVIP

中国科技论文在线 成人女性寰椎朗格汉斯细胞增多症一例及 文献复习# 赵耀东，薛亚军，楼美清* 5 （同济大学附属第十人民医院，上海 200072） 摘要：女性 26 岁患者，因“头痛 10 年，加重 3 月”入院。神经系统查体阴性，但颈部活动受 限。CT 扫描提示右侧颈静脉孔区溶骨性病变，增强后占位增强明显，但不甚均一。MRI 提 示 T1WI 等信号病变，增强明显。术前考虑郎格罕细胞增生症可能。随后在全麻下行病变切 除术。术中发现肿块呈暗红色，约 3.5 × 5.5 × 6 cm 大小，予以全切除。肿块边界清楚，起 10 源于寰椎，质地韧，血供丰富。术后病理证实为郎格罕细胞增生症。 关键词：寰椎；郎格罕细胞增生症；个案报道 中图分类号：R6 Langerhans cell histiocytosis of the atlas in a female adul 15 Zhao Yaodong, Xue Yajun, Lou Meiqing (Shanghai tenth peoples hospital, Tongji Universtiy, School of Medicine, ShangHai 200072) Abstract: A 26-year-old woman complained of headache for ten years, with aggravation for 3 months. No neurological deficits were observed. Physical examination demonstrated obvious restriction of the neck motion. CT examination confirmed a sharply osteolytic lesion of the right 20 posterior lacerate foramen area, after enhancement, the tumor mass density overall increased obviously, but not very uniform. On MRI, the soft-tissue mass is isointense on T1, but it enhances homogeneously after contrast administration. Based on the described radiological features of the bone deficit, an initial diagnosis of langerhans cell histocytosis was proposed. Under general anaesthesia a grey-red tumor of approximately 3.5 × 5.5 × 6 cm was completely removed from the 25 atlas. Tumor had a tough texture with clear border and abundant blood supply. Histopathologically, it was proved to be langerhans cell histocytosis. Keywords: atla