神经病理性疼痛相关microRNAs在感觉神经传导通路中功能研究.pdf

1 2 Abstract………………………………………………………………………………………………………………．7 3 ACCNGFAnteriorN-terminalNerveMAPKNMDAmGluRmentalBDNFBilateralBrain-derivedDEPCDRGDorsalDiabeticnervebCCIFBSPHNPPNPCRFetalbovinePainPbromiderootEBERKGABAGEFExtracellularXGTPaseGuanineEithidiumCREBCGRPCtLrPRISCkinaseCalcitoninrelatedkinasesretardationnucleotidekinaseRNAskinasesChainReactionRNA—induceduDRandomizedCaMKSPSPFacidacidSubstancecortex3factorfactorfactorfreechronicconstrictiontrialcontrolledthresholdcAMPsciaticserumlncRNASIKT