离体大鼠心肌顿抑模型的建立.docVIP

离体大鼠心肌顿抑模型的建立 作者：姚立农，柴伟，赵晖，杨永慧 【关键词】 缺血再灌注损伤 　　【Abstract】 AIM: To establish a myocardial stunning model of isolated rat heart by the Langendorff apparatus and identify its reliability. METHODS: 30 rat hearts were infused by KH perfusion solution and were divided to 5 groups by different periods of myocardial ischemia. Myocardial contractile and diastolic functions were measured during experiment and the infarct size was analyzed by TTC staining after reperfusion. RESULTS: There were significant differences in the myocardial function among all the groups during r