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What is dementia? Dementia is a group of brain disorders that disturb and damage cognitive (power of knowing) functions, affecting memory, one’s very personality, judgment, mood and social functioning . Cognitive function refers to all mental tasks we perform every minute from remembering our name to doing mathematical calculations. Memory is the often the first to go. Gradually one will also lose abilities of problem-solving ability, decision-making, judgment, managing physical space, putting words together communicating. Dementia is a permanent, progressive disease that affects mostly people after 50-55 years It is estimated that up to 4 million Americans suffer from AD. The National Institute of Aging estimates that the current cost of the care for AD patients is $100 BILLION a year, and this will increase with an aging population. The disease usually begins after age 60, and risk goes up with age. About 10 percent of men and women ages 65 to 74 have AD, and nearly half of those age 85 and older may have the disease. It is important to note, however, that AD is not a normal part of aging. blood pressure lowering may protect against dementia by preventing silent brain infarcts is plausible. The Lancet, Volume 353, Issue 9148, Page 237, 16 January 1999 The use of angiotensin converting enzyme (ACE) inhibitors, with or without diuretics, resulted in decrease incidence of stroke-related dementia, but dementia without stroke was not reduced. With the dihydropyridine calcium antagonists, a reduction in both Alzheimers type and vascular dementia was demonstrated . J Neurol Sci. 2004 Nov 15;226(1-2):71-4. The extended follow-up of Syst-Eur patients reinforces the evidence that blood pressure– lowering therapy initiated with a long-acting dihydropyridine protects against dementia in older patients with systolic hypertension. Arch Intern Med. 2002;162:2046-2052 Know About Dementia Hua fu Department of Cardiorenal and Cerebrovascular Me