某院292例药品不良反应报告分析.pdfVIP

2 0 1 3 年 3 月 第 3 卷 第 6 期 ·医药监管· 某院292例药品不良反应报告分析 林丽英 福建省龙岩人民医院药剂科，福建龙岩 364000 [摘要] 目的 了解我院药品不良反应（ADR）发生的特点及规律。 方法 对我院 2012 年 1~12 月上报的 292 例 ADR 报告进行回顾性分析。 结果 在 292 例 ADR 报告中，年龄≤ 20 岁的患者所占的比例为 18.84%，老年人 ADR 的构 成比为 27.74%；而注射剂是引发 ADR 的主要剂型，占总例数的 84.25%，抗菌药物引发的 ADR 占 31.51%，其次是 中药注射剂，占 19.18%；在临床表现方面，以皮肤及其附件损害最常见，占 34.34%。 结论 临床用药应关注小儿及 老年患者等特殊人群，同时应加强抗菌药物及中药注射剂的使用管理，提高药物临床合理应用水平，减少 ADR 的 发生。 [关键词]药品不良反应；合理用药；报告；分析 [中图分类号] R97      [文献标识码] B      [文章编号] 2095-0616（2013）06-141-02 Analysis of 292 cases of ADR reports in our hospital LIN  Liying Department of Pharmacy,Longyan Peoples Hospital in Fujian Province, Longyan 364000,China [Abstract] Objective To study the characteristics and regularity of adverse drug reaction(ADR) in our hospital. Methods 292 ADR cases repoted by our hospital during 2012January-December were analyzed retrospectively. Results Of the total 292 cases,aged 20 or less of the proportion of patients was 18.84%,the elderly constitute 27.74% of ADR but most of ADR were caused by injection,accounting for 84.25%;antibacterial drug ADR caused by 31.51%;Followed by traditional Chinese injection;accounting for 19.18%;main clinical manifestations were lesion of skin and appendants,accounting for 33.33%. Conclusion Clinical medicine should focus on children and elderly patients with special people,at the same time clinical should strengthen antibacterial drugs and traditional Chinese medicine injection use management,improve the clinical rational drug application level,reduce the occurrence of ADR. [Key words] ADR;Rational drug use;Report;Analysis 为了解我院 ADR 发生的情况，为临床安全合理用药提 占 84.25%，引发 ADR 的剂型分布见表 3。 供帮助，笔者通过对 2012