表观遗传学(epigenetics).pdf

1、表观遗传学(epigenetics) • 表观遗传学是研究不涉及DNA序列改变的基因表达和调 控的可遗传修饰,即探索从基因演绎为表型的过程和机制的 一门新兴学科。 或: 是针对不涉及到DNA序列变化而表现为DNA 甲基化谱、 染色质结构状态和基因表达谱在细胞代间传递的遗传现象的 一门学科。 或: 研究生物体或细胞表观遗传变异的遗传学分支学科。 • Epigenetics is typically defined as the study of heritable changes in gene expression that are not due to changes in DNA sequence. • Riggs and colleagues defined epigenetics as “the study of mitotically and/or meiotically heritable changes in gene function that cannot be explained by changes in DNA sequence” (1)表观遗传变异(epigenetic variation) 表观遗传 Epigenetic

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