Should I have an H1N1 flu vaccination after分析课件.pdf

A classic to get views & R eviews your teeth into, p 637 Should I have an H1N1 flu vaccination after Guillain-Barré syndrome? PERSONAL VIEW Laura Claire Price have found myself asking the difficult (risk ratio 1.45 (95% confidence interval 1.05 Campylobacter jejuni and cytomegalovirus, question of whether to be vaccinated to 1.99; P=0.02), although no such increase although in 60-70% of cases no causative against H1N1 flu when I return to work as a in risk was seen in a smaller UK study. Several organism is identified. Flu is a rare cause, hospital doctor this autumn. In December studies showed an increased risk of adverse thought to result in 1% of cases, although the 2008 I developed severe Guillain-Barré i events after flu vaccination, with 0.7 reports proportion is likely to increase during seasonal syndrome but am making a good recovery. of the syndrome per million vaccinations from outbreaks. Flu is likely to contribute to those I presented with foot drop one week 1990-2005, although these studies relied on cases where no causative organism is usually after an episode of food poisoning. Nerve case reporting so may be unreliable. identified, as suggested by a French study, in conduction studies showed patchy motor nerve Just two questionnaire based studies have which recent flu-like illness was reported in 30% demyelination and marked conduction block. examined the risk of recurrent Guillain-Barré of these cases. Of these patients, 14% tested I was admitted to the intensive care uni