Effect of naphthalene acetic acid on proliferation and apoptosis of mice hepatocytes.pdfVIP

· 450· 宦 痘堂塑旦王 堂苤查— 910 5月第 19卷第5期 ChinJGastroenterolHepatol，May2010，Vo1．19，No．5 Effectofnaphthaleneaceticacidonproliferation and apoptosisof micehepatocytes CUIJing，ZHONGJinyi，SUNQiaoping DepartmentofToxicology，MedicalCollegeofQingdaoUniversity，Qingdao266021，China 【Abstract】 Objective Toinvestigatetheeffectofnaphthaleneaceticacid(NAA)onproliferationandapoptosisof micehepatocytes．M ethods Fiftymicewererandomlydividedintofivegroups：positivecontrol，normalcontrol，low， middleandhighdoseofNAA groups．Miceinlow，middleandhighdoseofnaphthaleneaceticacidgroupswerefedwith 200 mg／