极固宁TM对全冠牙体预备后牙髓组织的影响_医学论文.docVIP

极固宁TM对全冠牙体预备后牙髓组织的影响_医学论文 极固宁TM对全冠牙体预备后牙髓组织的影响_医学论文 作者：陈素凤， 程辉， 郑志强， 姚丽艳， 龙学辉， 郑明 【关键词】 抗变态反应药；,金属烤瓷合金；,牙冠（假体）；,牙本质；,牙髓 　　摘要:目的 观察极固宁TM涂布于金属烤瓷全冠活髓基牙牙预备体表面21 d对牙髓组织学形态的影响。方法 选择因正畸治疗需要而计划拔除的20颗前磨牙进行金属烤瓷全冠牙体预备，其中每2颗牙均为同颌同名牙；采用随机、双盲、自身对照设计分为2组：对照组在牙预备体上直接用氧化锌丁香酚水门汀粘固暂时冠；观察组在牙预备体上涂布极固宁TM后用氧化锌丁香酚水门汀粘固暂时冠。所有牙分别于牙体预备后21 d拔除，常规组织病理切片，HE染色，显微镜下观察评价牙髓组织反应。结果活髓基牙经金属烤瓷全冠牙体预备21 d时，对照组和观察组的牙髓组织反应无明显差别(P＞0.05)。牙髓组织的反应程度与牙预备体的剩余牙本质厚度（RDT）有关；RDT分别为491.76，503.88和487.32 μm的3个样本观察到修复性牙本质的形成。结论 在本实验条件下，金属烤瓷全冠牙预备体表面涂布极固宁TM21 d对活髓基牙的牙髓组织无明显影响。 　　关键词: 抗变态反应药； 金属烤瓷合金； 牙冠（假体）； 牙本质； 牙髓 　　ABSTRACT: Objective To observe vital pulp response after 21 days of Green Or applied to the surface of PFM crown preparations.Methods 20 human biscuspids scheduled to be extracted for the orthodontic reasons were prepared for porcelain fused to matal(PFM) crown,of which every 2 teeth were from the same patient and the same jaw. The teeth were randomly， blindly and selfcontrolly divided into 2 groups.In the control group：the temporary crowns were cemented with zinc oxide cement.In the testing group：Green Or was applied before the temporary crowns were cemented with zinc oxide cement. After 21 days the teeth were extracted and prepared according to normal histologic techniques.Serial sections were stained with HE. The intensity of the pulp response was evaluated by light microscope. Results There was no statistical difference in the inflammatory response between the control group and the testing group(P＞0.05). The intensity of the pulp reaction was correlated with the remaining dentin thickness(RDT).The RDT of the three specimens，which showed deposition of reparative dentine，was 491.76, 503.88 and 487.32 μm. Conclusion Based on the experimental conditions，Green Or has little effect on the histopathologic response of the vital pulp at day 21 after PFM crown preparations. 　　KEY WORDS:metal ceramic alloys crowns dental pulp 　　金属烤瓷全冠修复体已经广泛应用于临床，然而其牙体预备时常常需要磨除大量的牙体组织，导致牙本质小管暴露，外界各种刺激通过暴露的牙本质小管传至髓腔，引起基牙过敏及牙髓炎等症状。据报