肝细胞腺瘤的临床诊治及文献复习_安松林.pdfVIP

第2 5 卷 肝 胆 胰 外 科 杂 志 第6 期 ·论 著 · 肝细胞腺瘤的临床诊治及文献复习 安松林，王黎明，荣维淇，吴凡，余微波，刘发强，冯莉，田斐，吴健雄 （北京协和医学院/中国医学科学院肿瘤医院 腹部外科，北京 100021） [摘 要] 目的 分析肝细胞腺瘤的临床特点及诊治经验。方法 回顾性分析我院2000年1月至2012年12 月外科切除并经病理诊断为肝细胞腺瘤的16例患者临床资料。结果 肝细胞腺瘤一般无明显症状，部分表 现为右上腹隐痛不适等非特异性症状。1例合并乙肝，1例合并乙肝及丙肝，所有患者AFP均为阴性。术前 诊断符合率为43.75%（7/16）。均接受手术治疗，随访10～160个月，1例术后130个月复发，再次手术后 健康存活，其余患者均健康生存。结论 肝细胞腺瘤好发于年轻女性，超重可能与发病有关，其临床表现 多不典型，常规影像学方法确诊率较低，CT、MRI增强扫描有一定诊断价值。手术切除是肝细胞腺瘤主要 的治疗方法。治疗后可复发，需定期复查。 [关键词] 肝细胞腺瘤；肝切除术；临床病理；预后 [中图分类号]R 7 3 5 .7 [文献标识码]A [文章编号]10 0 7 - 19 54 (2 0 13) -044 8-05 Clinical and pathologic features and surgical treatment of hepatocellular adenomas AN Song- lin, WA N G L i-m ing , R ON G Wei-q i, et a l. D ep artment of A bdominal Surg ery, Cancer H osp ital, Chinese A cademy of M edical Sciences, P eking Union M edical Colleg e, B eij ing 10002 1, China Abstract Objective To explore clinical and pathologic features, diagnosis and surgical treatment of hepato- cellular adenomas (HCA). Methods A retrospective clinical analysis was made in 16 hepatocellular adenomas confirmed pathologically admitted from Jan . 2000 to Dec. 20 12 . Results No specific clinical features were identified. One case was with hepatitis B viru s infection and another was with hepatitis B virus combined with hepatitis C viru s infection . Alpha fetoprotein (AFP) was negative in all the patients. Only 7 in the 16 cases were correctly diagnosed by imaging examinations preoperatively . Surgical treatment was performed in all the patients with Ro resection and the outcome was satisfactory. During the follow-up period of 10~ 160 mon, 1 case under- went reoperation which recurred 130 mon after the first operation, while the other 15 cases were healthy without recurrence or malignant transformation. Conclusion