植物microRNA研究进展.pdfVIP

HEREDITAS (Beijing) 2007 3 , 29(3): 283―288 ISSN 0253-9772 综述 DOI: 10.1360/yc-007-0283 microRNAs 1 2 1 2 2 李培旺 , 卢向阳 , 李昌珠 , 方俊 , 田云 1. , 410004 2. , 410128 : 植物microRNAs(miRNAs)是一类与RNA 诱导沉默复合体相关的约由22 个核苷酸组成的单链小RNA 分 子, 其主要功能是, 通过特异性剪切靶 mRNA 或阻遏靶 mRNA 的正常翻译在转录后水平调控基因的负表达。 植物miRNAs 的靶标主要是参与调控植物生长发育和防御应答的转录因子家族。文章主要综述miRNAs 在植物 体内的生物发生、作用机制及其调控作用研究新进展。 : 植物microRNAs; 转录后基因调控; 植物生长发育。 Advances in the study of plant microRNAs 1 2 1 2 2 LI Pei-Wang , LU Xiang-Yang , LI Chang-Zhu , FANG Jun , TIAN Yun 1. Hunan Forestry Academy, Changsha 410004, China; 2. Biochemistry Fermentation Lab of Life Science, Hunan Agricultural University , Changsha 410128, China Abstract: Plant microRNAs (miRNAs) are single-stranded RNA molecules of around 22 nucleotides (nt) in length that are associated with the RNA-induced silencing complex (RISC). They act as post-transcriptional negative regulators of gene expression mainly by guiding cleavage or attenuating the translation of target transcripts. The targets of plant miRNAs often belong to transcription factors families involved in the control of developmental processes and defense responses. In the present paper, we reviewed the recent advances in our understanding of the biogenesis and mechanism of action of plant miRNAs, as well as the regulatory roles in plants. Keywords: plant microRNAs; post-transcriptional gene regulation; plant growth and development MicroRNAs(miRNAs) 1925 RNA 1993 , LeeWightman[1,2] 1 microRNAs mircoRNA lin-4, , 1.1 microRNAs , microRNAs3 : microRNAs[3~6], RNA microRNAs ,