包覆甲氧基肉桂酸辛酯固体脂质微粒的制备及性能.pdfVIP

第 62卷 第 1O期 化 工 学 报 VoI．62 No．10 2011年 1O月 CIESC Journa1 October 2011 T1了 包覆 甲氧基肉桂酸辛酯固体脂质微粒的制备及性能 张婉萍，牛文霞 (上海应用技术学院香料香精技术与工程学院，上海 200235) 关键词 ：固体脂质微粒 ；甲氧基 肉桂酸辛酯 ；防晒剂 ；紫外吸收 DOI：10．3969／i．issn．0438—1157．2011．10．041 中图分类号 ：TQ658 文献标 志码 ：A 文章编号 ：0438—1157 (2011)10—2964一O5 Preparation and characterization ofsolid lipidnanoparticles loaded octylmethoxycinnamate ZHANG W anping。NIU W enxia (SchoolofPerfumeandAromaTechnology，ShanghaiInstituteofTechnology，Shanghai200235，China) Abstract：Preparationandpropertiesofsolid lipidnanoparticlescarriedoctylmethoxyeinnamate (OMC) werestudied．Theinfluenceofoctylmethoxycinnamate (OMC) andpH valueon thedistribution，size， Zeta potential of solid lipid nanoparticle were studied．M eanwhile the configuration， particle size， compositionandsunscreenpropertieswerecharacterized．TheresultshowedthattheZetapotentialofsolid lipidnanoparticlewasabout40 mV withoptimizing compositionandmiddleorweak basicpH condition． Theaverageparticlesizeofsolid lipidnanoparticlewasabout150nm and theparticledistributionwas homogeneous．Particleconfiguration was sphericalwith or withoutOM C and little flocculation．Carried OMC increasedtheparticlesize．OM C with lipidmaterial，emulsifierformed thesolid 1ipidnanoparticle togetherbutnotcarriedinthecore．ThesolidlipidnanoparticlewithOMC havegoodultravioletadsorption andthesynergyfunctionwasbetweenthesolidlipidnanoparticlesandsunscreen． Keywords：solidlipidnanoparticle；octylmethoxycinnamate；sunscreen；UV absorption L．