冠状动脉生物可降解支架设计与应用：材料学的进一步革新将带来什么？.pdfVIP

中国组织工程研究 第 18 卷 第30 期 2014 –07 –16 出版 Chinese Journal of Tissue Engineering Research July 16, 2014 Vol.18, No.30 www.CRTER.org Design and application of biodegradable coronary stents: what will be brought by further innovations in materials science? Chen Jia-hui, Shen Li, Wang Qi-bing, Ge Jun-bo Department of Cardiology, Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai 200032, China Abstract BACKGROUND: With the social and economic development and aging, coronary heart disease has become Chen Jia-hui, Studying for the primary cause of death endangering human life and health, while cardiovascular intervention (especially master’s degree, Department stenting) in the treatment of cardiovascular disease is at a growing status. of Cardiology, Zhongshan OBJECTIVE: To describe the development, research progress and latest clinical application of heart Hospital, Shanghai Institute of Cardiovascular Diseases, interventional materials as well as advantages and disadvantages of biodegradable stents, and meanwhile to Fudan University, Shanghai prospect for its future development and improvement. 200032, China METHODS: A computer-based online search was conducted in PubMed for English language publications from January 1999 to April 2014 using the key words of “stent, scaffold, bioabsorbable, bioresorbable, biodegradable, Correspondin