Meta分析的应用.pptVIP

The Practice of Meta-Analysis Raymond J.G.M. Florax Henri L.F. de Groot ? Florax/de Groot 2002 * Outline Operational issues - database - software and type analysis Practice of meta-analysis - value transfer - alternatives to meta-analysis - prospect and significance of meta-analysis ? Florax/de Groot 2002 * Operational issues – I Database development and initial analyses - spreadsheet (MSExcel) - use available options (descriptive stats, graphs, pivot table/charts for contingency tables) - calculation of simple tests (Q-test) - combining p-values - compute fixed effects average ? Florax/de Groot 2002 * Operational issues – II Advanced statistical software - choose software in relation to type analysis - see websites for overview of software http://www.prw.le.ac.uk/epidemio/personal/ajs22/meta/book.html /archive/7126/7126ed9.htm - software may not be appropriate in non-experimental context ? Florax/de Groot 2002 * Operational issues – III Tailored software (watch out for applicability) Macros of general packages for “classical” analysis - SAS (note: Arthur et al. (2001), Conducting meta-analysis using Sas) - Stata (see newsletter) WinBUGS for Bayesian analysis General software - Eviews, Limdep, SPSS, etc. ? Florax/de Groot 2002 * Practice of doing meta-analysis Meta-analysis and value transfer Alternatives to meta-analysis Prospects and significance of meta-analysis ? Florax/de Groot 2002 * Value transfer – I Transfer of results for (a) studied site(s) to unstudied sites Synonymous to “benefit transfer” Advantages - cost effective - improved use of information Used in policymaking - USA: EPA (value of life), NOAA (spills) - UK: landfill tax ? Florax/de Groot 2002 * Value transfer – II Different types of value transfer: - (mean) value - demand or bid function (“function transfer”) - value or function based on meta-analysis Accuracy results is (still) disappointing - just transferring values is na?ve - use meta-an