心血管外科手术患者预防性应用质子泵抑制剂点评分析.pdfVIP

心血管外科手术患者预防性应用质子泵抑制剂点评分析 阳丽梅, 黄旭慧 ，郑 璇 ，蔡柔荧1 1 1 2 (1福建医科大学省立临床医学院/福建省立医院，福州 350001;2 福建省立医院北院/福 建省老年医院，福州 350001) 摘要：目的：对心血管外科手术患者预防性应用质子泵抑制剂（PPI）的使用情况进行专项 点评。方法：选择2012年1~4月自我院心血管外科出院的手术患者，设计《心血管外科手术 患者预防性应用PPI点评表》，根据指南及药品说明书制定点评标准，对PPI使用情况进行专 项点评。结果：总共点评229份病历，其中187份使用了PPI，使用率为81.7%，泮托拉唑的使 用频次最高；专项点评结果显示，疗程过长是最常见的不合理用药表现，另外还存在用药频 次错误、无指征更换药物、存在明显相互作用、重复用药、无适应证用药及溶媒选择错误等 不合理现象。结论：本次专项点评为干预措施的制定提供了数据支持，根据点评结果制定相 应的干预计划，并持续改进，促进合理用药。 Specialized Prescription Comment on Prophylactic Application ofProtonPumpInhibitorinCardiovascularSurgeryPatients 1 1 1 2 YANG Li-mei ， HUANG Xu-hui , ZHENG Xuan , CAI Rou-ying (1. Fujian Provincial ClinicalCollegeofFujianMedicalUniversity/FujianProvincialHospital，Fuzhou350001，China; 2. Fuzhou 350001，China;2. North Hospital of Fujian Provincial Hospital/ Fujian Geriatri Hospital,Fuzhou350001，China) Abstract: AIM To conduct a specialized prescription comment on patients who were prescripted propon pump inhibitors( PPIs) in cardia surgery. METHODS Patient discharged from cardia surgery between January and April 2013 were chosen, a form was designed for specialized prescription comment on PPIs, indexes were set a ording to literatures and instructions,andprescriptioncommentwasconduct.RESULTSTotal229caseswerecommented, of which 187cases(81.7%) used PPIs, among all of PPIs , pantoprazole was most frequently used. Results from comment showed that the most frequently irrational drug use was that the durationwastoolong,inaddition,therewereotherirrationaldrugphenomena,suchasmedication frequencyerrors,non-indicationsofreplacementdrugs,significantinteractions,non-indicationsof PPIsuseandsolventerrors.CONCLUSIONThiscommentsuppliedevidencefordevelopmentof 563 interventions.Weshoulddrawupaplanforinterventionsandpromoteclinicalrationaldruguse. 质子泵抑制剂(pro