肿瘤测序基因.xlsVIP

Sheet3 Sheet2 Sheet1 Gene Symbol Gene Name Ocogene score* Classification* Core pathway Process Mutated Tumor Samples** JAK2 Janus kinase 2 Oncogene STAT Cell Survival KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog RAS TP53 tumor protein p53 TSG Cell Cycle/Apoptosis; DNA Damage Control BRAF v-raf murine sarcoma viral oncogene homolog B1 Tumor Suppressor Gene（TSG） score* EGFR epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) PI3K; RAS CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa APC Cell Fate adenomatous polyposis coli FLT3 fms-related tyrosine kinase 3 RAS; PI3K; STAT KIT similar to Mast/stem cell growth factor receptor precursor (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen); v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog PI3K; RAS; STAT NRAS neuroblastoma RAS viral (v-ras) oncogene homolog NPM1 nucleophosmin 1 (nucleolar phosphoprotein B23, numatrin) pseudogene 21; hypothetical LOC100131044; similar to nucleophosmin 1; nucleophosmin (nucleolar phosphoprotein B23, numatrin) Cell Cycle/Apoptosis PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide PI3K PTEN phosphatase and tensin homolog; phosphatase and tensin homolog pseudogene 1 VHL von Hippel-Lindau tumor suppressor CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) ABL1 c-abl oncogene 1, receptor tyrosine kinase ASXL1 additional sex combs like 1 (Drosophila) Chromatin Modification CEBPA CCAAT/enhancer binding protein (C/EBP), alpha PI3K; RAS; MAPK DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha FBXW7 F-box and WD repeat domain containing 7 NOTCH FGFR3 fibroblast growth factor receptor 3 PI3K; RAS ; STAT FOXL2 forkhead box L2 TGF-b GATA1 GATA binding protein 1 (globin transcription factor 1) GNAQ guanine nucleotide binding protein (G protein), q polypeptide PI3K;RAS; MAPK GNAS GNAS complex locus APC; PI3K; TGF-b, RAS Cell Survival/Cell Fate H3F3A H3 histon