点阵CO2激光论文：点阵CO_2激光联合积雪苷霜软膏治疗痤疮凹陷性瘢痕疗效观察.docVIP

点阵CO2激光论文：点阵CO_2激光联合积雪苷霜软膏治疗痤疮凹陷性瘢痕疗效观察 【中文摘要】选用点阵CO2激光联合积雪苷霜软膏的方法治疗痤疮凹陷性瘢痕,旨在评价联合治疗对痤疮凹陷性瘢痕的临床疗效和安全性,掌握点阵激光的临床适应证及应用技巧,探索一种安全性高、疗效可靠、误工期短、适宜推广的治疗痤疮瘢痕的新方法。方法：所选40例患者均为2009年12月至2011年03月江苏省中医院皮肤科门诊患者,随机将40例患者分为两组,点阵C02激光联合积雪苷霜软膏组为治疗组,单一点阵C02激光组为对照组,每组各20例,两个月左右治疗一次,两次为一个疗程。遵循B.Dreno的ECCA权重评分表,根据痤疮瘢痕的性状和密集程度进行权重评分,观察两次治疗后皮损变化情况并作出评分,记录治疗中和治疗后所出现的不良反应及持续时间,从而做出疗效评价及安全性评价。结果：1.治疗组有效率75%,对照组有效率65%,两组总有效率比较,差异无统计学意义(P=0.4900.05)；2.治疗组误工期为7.89±3.39天,对照组误工期为10.58±3.90天,治疗组明显低于对照组,有统计学意义(P=0.030.05)；3.不论治疗组还是对照组,两次治疗疗效均好于一次治疗疗效；4.治疗过程中发现的常见不良反应包括：红肿、灼热、轻微疼痛,出现几率100%；少见不良反应包括：色素沉着1例、持久性潮红1例、感染性脓疱3例。未见严重的不良反应。结论：研究证实了点阵CO2激光联合积雪苷霜软膏治疗面部痤疮凹陷性瘢痕疗效可靠,其临床疗效与单一点阵CO2激光治疗无明显差异,但治疗组误工期明显缩短。两组均未出现严重不良反映,说明点阵C02激光在治疗痤疮凹陷性瘢痕上安全有效,联合积雪苷霜软膏治疗能够有效地缩短误工期,值得推广。 【英文摘要】:The objective is to use the way of combining Fractional CO2 Laser and Centella Triterpenes Cream to treat face atrophic acne scar, and to evaluate the efficacy and safety of combining treatment way. Master the clinical indications and applications of Fractional Laser. Want to be able to seek a safe, effective and suitable for promotion way in the treatment of atrophic acne scars.Methods:40 patients were selected from December 2009 to March 2011 in Dermatology Clinic of Jiangsu Province Hospital of TCM,40 patients were randomly divided into two groups,The combined of fractional CO2 Laser and Centella Triterpenes Cream is as treatment group, a single fractional CO2 Laser group is as the control group,20 patients in each group, Treatment once every two months, twice is as a course of treatment. Follow the ECCA score sheet weight, according to the traits of acne scars and intensity of the weights score, observed changes in the two treated lesions, and to score and record the treatment and treatment of adverse reactions which occurred after and duration thus making evaluation of efficacy and safety evaluation.Results:1. The effectiveness of Treatment group is 75%,the control group is 65%, with similar efficiency, no statistically sign