痰热清联合阿奇霉素治疗4＇，JL支原体肺炎疗效观察.pdfVIP

维普资讯 垫茎垒壹2006年第12卷第5期JournalofPediatricPham1acv2006，V01．12，N0．5 · 37 · 痰热清联合阿奇霉素治疗4,JL支原体肺炎疗效观察 吴伟 明，陈丽佳，陈 靖 ，鲍仕 慧 (温州医学院附属第二医院，浙江温州 325027) [摘要]目的：观察痰热清注射液联合阿奇霉素治疗小儿支原体肺炎的临床疗效和安全性 。方法 ：将 90例支原体肺炎患儿随机分 为两组 ：对照组45例采用阿奇霉素序贯疗法治疗 ，治疗组 45例在对照组治疗基础上加用痰热清注射液静脉点滴治疗 ，并对临床 疗效和安全性指标进行 比较 。结果 ：治疗组和对照组总有效率分别为86．7％和 64．4％，两组总有效率 比较差异有统计学意义 (P 005)；但两组治愈率 比较差异无统计学意义(P005)；治疗组的主要}J各床症状缓解时间及住院时间明显短于对照组 (P 0．05)；治疗组不良反应发生率较对照组低 (P005)。结论 ：痰热清联合阿奇霉素治疗小儿支原体肺炎效果显著，不 良反应少： [关键词]痰热清注射液；阿奇霉素 ；支原体肺炎 [中图分类号]R7256 [文献标识码]B [文章编号]1672—108X(2006)05—0037—03 Clinicalobservation ofintravenousTanreqing and azithromycin in treating pediatric patients 、vith mycoplasma pneumonia WUWei—uring，CHENLi—jia，CHENJing，etal(TheSecondAffiliatedHospitalofWenzhouMedicalCollege．ZhejiangWenzhou 325027，China) A【bstractjObjective：ToinvestigatetheclinicaleffectandsafetyofintravenousTan．reqinginjectionwithazithromycinintreatmentofchildren withmycoplasmapneumonia(MP)．Methods：90casesofchilrdenwithMPinfectionwererandomlydividedintotwogroups：therteatmentrgoup (45cases)receivedthecombinativetherapyofTan．reqinginjectionandazithromycin，whilethecontrolrgoup(45cases)receivedthesequential therapyofonlyazithromycin，andthencomparisonwasmadebetweentworgoupsinclinical effectsandadversereactions．Results：Athteendof therteatmentprorgam，thetotalvalidrateofhteobservedrgoupwas86．7％ andthatofthecontrolrgoupwas46 ．4％ (P0．05)．Buttwo groupsdidnothavesignificantdiscrepancyonthecurerate(P0．05)．Andthetimeforrelievingthemainsymptomsandthetimeinhospital wereobviouslyshorterintreatmentrgoupthanincontrolgroup (P0．05)．Andtheadversereactionsintreatmentrgoupwassignificantlyless thanincontrolgroup(P0．05)．Conclusions：ThecombinativetherapyofTanr．eqinginjectionandazithromyeinismoreeffectivewithless adversereactionsthansingleazihtmmyeinintreatingchilrdenwithMP． 【KeywordsjT