结核性脑膜炎脑脊液细胞学动态观察的临床意义_何俊瑛.pdfVIP

《》　2004 115 19 21 　Clinical Focus, November 5, 2004, Vol 19, No.21 ·1225 · ·· 1 2 1 1 1 1 何俊瑛 ,刘秀丽,卜　晖 ,巩　忠,金便芬 ,许文华 (1. , 050000;2. , 053000) 　　　:　探讨脑脊液细胞学动态观察在结核 脑膜炎中的临床应用价值。　通过脑脊液细胞学检测 方法对43 例结核 脑膜炎组及47 例对照组进行动态观察, 分析结核 脑膜炎在不同时期所具备的特点和持续的时 间, 并通过脑脊液细胞学演变过程的分析评估治疗的效果。　典型的结核 脑膜炎早期呈以粒细胞增多为主的 混杂细胞反应, 治疗中期粒细胞逐渐减少, 免疫细胞、激活单核细胞增多, 治疗晚期以激活淋巴细胞反应为主, 粒细胞 逐渐消失, 治愈后细胞学恢复正常, 并可以此与化脓 脑膜炎、病毒 脑膜炎、隐球菌 脑膜炎等鉴别, 对结核 脑膜 炎的预后也有重要的指导意义。　脑脊液细胞学的动态监测有助于结核 脑膜炎的早期快速诊断, 并在结核 脑膜炎患者的预后判断上有 一定价值。 :结核 脑膜炎;脑脊液;细胞学 :R529.3　:A　:1004-583X(2004)21-1225-04 Dynamic observationof cerebrospinal fluid cytology ontuberculous menigitis ＊ HE Jun-ying , LI Xiu-li, P Hui, GONG Zhong, JIN Bian-fen, X Wen-hua ＊ Dop ar tmen t of Neurology , th e S econd Hosp ital of H ebei Med ica l Un iversity , S hij iaz huang 050000, China ABSTRACTS:Objective 　To discuss the clinical value of cerebrospinal fluid cytology dynamic observation on tuberculous menigitis.Medthods　The dynamic detection of cerebrospinal fluid cytology was applied to 43 patients with tuberculous menigitis and 47 control patients, analysing the character and duration of different periods in tuberulous meningtis and assessing the curative effect were conducted through analysing cerebrospinal fluid cytology evolvement.Results　The representive tuberculous menigitis in forepart showedintermix cytology reaction which had the most granulocytes.During the middle period of the treatment, granulocytes reduced and immune cells and active hyaline leukocytes increased.During the later period of the treatment, active lymphocytes reaction was the most obvious.Cerebrospinal fluid cytology was normalwhen tuberculous menigitis