Nitro_PAPS直接光度法测定葡萄糖酸锌含量_曹高忠.pdf

# 270# 安 徽 医 药 A nhuiM edical and Pharm aceutical ournal 2006 A pr; 10( 4) N itro-PAPS直接光度法测定葡萄糖酸锌含量 1 2 1 , , ( 1. 浙江省温州医学院附属第一医院药剂科, 浙江 温州 325000; 2. 浙江省温州永嘉县中医院药剂科, 浙江 永嘉 325100) : ( T r itonX-100) , 2-( 5--2-) -5-[ N--N-( 3- ) ] ( N itro-PAPS ) 576 nm, 0 ~ 10Lg / 10 m , 1. 26@ 105 L# mo - 1 # cm- 1, 99. 2% ~ 101. 7% , , : ; N itro-PAPS; Nitro-PAPS direct spectrophotometricmethod to determine Zinc Gluconate CAO Gao-zhong, TANG Dong- cheng, L IU A i-yue (The D ep artm ent of Pharmacy, The F irstAff iliated H osp ital of WenzhouM ed ical College, W enzhou 325003, China) Abstract: A im T o estab ish a s mi p e, sens itive and stab e new m ethod o f de term ining Z inc G ucona te. M ethods 2-( 5-nitro-2-pyr idy- azo) -5-( N-propy-N-3- su fopropy am ino) pheno w as u sed as a co oring reagen t to determ ine zinc g uconate by spectropho tom etry in the presence o f surfactan ts T r iton X- 100. Results T he m ax mi um abso rption o f the com p ex compound w as a t 576 nm. T he inear ity of test 5 - 1 - 1 w as 0 ~ 10L g / 10m . The mo ar abso rption coeffic ient is 1. 26 @ 10 L# m o # cm . T he recover ies ranged from 99. 2% to 101. 7% . Conclusions Th is m ethod is s mi p e, sens itive, rap id and accurate. The m e thod cou d be u sed for the determ ination of Z inc in Z inc G u- conate so ution w ith sa tisfactory resu ts. K ey words: Z inc G uconate; N itro- PAPS; spectropho tom etry , , , ,