S_180_肉瘤_艾氏腹水瘤肿瘤移植模型建立的研究_叶明霞.pdfVIP

2002 2 February, 2002 12 　 1 CHINESE JOURNAL OF LABORATORY ANIMAL SCIENCES Vol.12　No.1 S , 180 叶明霞　周顺长　孔利佳　任大宏1 (, 　4 00 0) 　　【】　　S180 , EAC , BALB c 、 。 　BALB c , BALB c , , , 10 d 。 　BALB c , , , ;, , , 。 　 。 【】　S180 ;EAC ; 【】Q95- 　　【】A　　【】1002-1485(2002)01-0014-0 Study on Establishing the Replanting Models of Strain S180 and EAC YE Mingxia, ZHOU Shunchang, KONG Lijia et al (Faculty of Laboratory Animal, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 4 00 0, China) 【Abstract】　Objective　To establish the replanting models of strain S180 and EAC using BALB c and Kunming mice re- spectively.Method　The mice were randomly divided into 4 groups with different treatment.After 10 days, we compared tumour weight and pathological changes.Result 　BALB c mice s model group showed apparent difference, compared with Kunming mice s, and there was very apparent difference of pathological changes between positive and model grouop.The tumour cellswere found transfering in the mices liver of these two model groups.Conclusion　Pathological diagnosis shows a significant reference value. 【Key words】　Strain S ;Strain EAC;Replanting model mice 180 　　。 1　 , , 。S180 1.1　 , EAC BALB c 1.1.1　 , 、 　　BALB c (n =40), 18 ～20 g, 。, , , : 、, :19—006。 , , 　　(n =40), 18 ～20 g, 、、 , , : 。 :19—052。 1.1.2　 1 　4 00 0