缺血性心律失常发生机制的研究进展.pdfVIP

·32 10 · 医 学综 述 2011 年 11 月第 17 卷 第 2 1 期 Medical Recapitulate, Nov. 2011, Vol. 17, No. 2 1 [ 18] Belaiba RS, Bonello S, Schmidt S, et al. Hypoxia up-regulates hy- [ 22] Laderoute KR . The interaction between HIF-1 and A P-1 transcrip- poxia-inducible factor-1 αtranscription by involving phosphati dyli- tion factors in response to low oxygen [ J] . Semin Cell Dev Biol, nositol3-Kinase and nuclear factor kappaB in pulmonary artery 2005 , 16( 4 / 5) : 502-5 13 . muscle cells [ J] . Mol Biol Cell , 2007 , 18 ( 12) : 469 1-4697. [ 23] Jiang J, Xia X B, X u HZ , et al. Inhibition of retinal neovasculariza- [ 19] Yun SP, Lee MY, Ryu JM, et al. Role of HIF- 1 αlpha and VEGF in tion by gene transfer of small interfering RNA targeting HIF-1 αlpha human mesenchymal stem cell proliferation by 17beta-estradiol : in- V EGF[ J] . J Cell Physiol, 2009, 2 18 ( 1) : 66-74. volvement of PKC, PI K /A kt, and MA PKs [ J] . A m J Physiol Cell 3 [ 24] Witmer AN, Vrensen GF, Van Noorden CJ, et al. Vascular endothe- Physi ol , 2009 , 296( 2) : 3 17 -326. lial growth factors and angiogenesis in eye disease [ J] . Prog Retin [ 20] Mottet D, Dumont V , De ccache Y , et al. Regulation of hypoxia- Eye Res, 2003 , 22( 1) : 1-29 . induc ible fac tor-1alpha protein level during hypoxic conditions [ 25] Wang X, Wang G, Wang Y . Intravitreous vascular endothelial growth by the phosphatidylinositol 3 -kinase /A kt / glycogen synthase ki- factor and hypoxia-inducible factor 1a in patients with proliferative nase 3 beta pathway in