高强度聚焦超声治疗子宫肌瘤MRI的临床与研究.pdfVIP

中国(第七届)肿瘤微创治疗学术大会 暨 世 界 影 像 导 引 下 肿 瘤 微 创 治 疗 学 会 成 立 筹 备 大 会 高强度聚焦超声治疗子宫肌瘤MRI的临床研究 胡军，张素敏，郭新婷，杨根增，吴丙丙，刘峰，李东风 河南省洛阳市第一人民医院， 471002 摘要 目的 方法 通过MRI及超声随访探讨高强度聚焦超声（HIFU）治疗子宫肌瘤的有效性。 60例经HIFU治疗的 子宫肌瘤患者，术前、术后分别在MRI上表现出T１加权像和T２加权像上的信号，并分别在术后1、3、6、和12个月进 结果 行超声复查，计算瘤体的均径和治疗前比较。 MRI显示HIFU治疗后子宫肌瘤组织表现为凝固性坏死，即在T２WI （T２加权像）呈低、高或稍高信号，和T１WI（T１加权像）呈低信号，超声随访显示治疗后1个月出现肌瘤缩小，3个月 结论 以后瘤体明显缩小，与治疗前相比有显著差异（P0.05）。 RMI检查和超声随访证实HIFU治疗子宫肌瘤的确有 效。 关键词 高强度聚焦超声 子宫肌瘤 MRI 随访 High Intensity Focused Ultrasound for Treatment of Uterine Leiomyoma:Clinic Study with MRI ， ， Hu Jun, Zhang Sumin Guo Xinting, Yang Genzeng,Wu Bingbing Liu Feng, Li Dongfeng Abstract: Objective To search the effects of high intensity focused ultrasound(HIFU)for uterine leiomyoma(ULMM)in which both MRI and ultrasound were useds. Methods: 60cases with ULMM were treated with HIFU which were studied by MRI of T1WI and T2WI imagine and were followed up by ultrasound before and 1,3,6 and 12 months after HIFU to compare the diamenters of the ULMM. Results: After HIFU the ULMM became coaggulatire necrosis as showed on MRI by low or higher image of T2WI and lower image of T1WI. Ultrasound follow up showed that the tumor began to shrink one month after HIFU ablation and the regression of ULMM was obvious three months after HIFU(p0.05). Conclusions: MRI examine and ultrasound follow up confirmed that the HIFU had an obvious effect on ULMM. Key words: High intensity focused ultrasound, Uterine leiomyoma, Pathology, F