《Association between hsamiR34bc rs4938723 T > C promoter polymorphism and cancer risk a metaanalysis based on 6036 cases and 6204 controls》.pdfVIP
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- 2015-09-03 发布于浙江
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Association
betweenhsa·miR一34b/crs4938723
TC
promoter
andcancerrisk:a basedon
polymorphism meta--analysis
6,036
casesand controls
6,204
Tao Chenl纳,BinXul’2’j’ChunhuiLiul,2’3Yiduo
T…a01触,Shuqiu Wan91”,Yeqing
Chenl’厶3
of Research
1DepartmentUrology,Affiliated of
ZhongdaHospital,MedicalSchool,2SurgicalCenter,MedicalSchool,’Institute
210009,China
University,Nanjing
*These
authorscontributedtOthiswork.
equally
210009,China.
Email:mingchenseu@gmail.com.
evidenceshowsthat astumor
or
Objective:Emerging microRNAs(miRNAs)function
suppressors
inhuman nucleotide inthe
oncogenes carcinogenesis.Asingle polymorphism(SNP)locatedpri—miRNA
affectthe and ofmature studiesshowed
promotermay processingexpression miRNA.However,previous
results t11eassociationof
conflicting hsa—miR一34b/crs4938723 TC
regarding promoterpolymorphism
witll
cancer.Therefore,weconducteda todetermine山eassociationof with
recta—analysis polym
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