丙泊酚中长链和长链脂肪乳对老年腹腔镜胆囊切除术患者肝功能和免疫功能的影响.pdfVIP

·76· 堡堂堕壅婴塞；!!!生!旦 笙!!鲞整!塑』垡堕垦塑：』!!：垫!!：!!!!!!些! ● 论著 ● 丙泊酚中长链和长链脂肪乳对老年腹腔镜胆囊切除术患者肝 功能和免疫功能的影响 周汾余剑波’ (天津市南开医院麻醉科，天津300100) [摘要]【目的】观察丙泊酚中长链和长链脂肪乳荆对老年腹腔镜胆囊切除术(LC)患者肝功能和免疫功能 的影响。【方法】行LC老年患者80例，ASAI～Ⅱ级，随机分为A，B两组，每组40人。A组采用1％长链脂肪乳 注射液行麻醉诱导和维持。B组采用丙泊酚中／长链脂肪乳注射液行麻醉诱导和维持。常规监测心电图、血压、 血氧饱和度。于术前、术后1h和术后24h测定肝功能及免疫功能的改变。【结果】B组术后24h肝功能血清丙 氨酸转移酶、天门冬氨酸转移酶、总胆红素低于A组；与B组相比，A组IgG明显下降，差异均有显著性(P 0．05)。【结论】丙泊酚中长链脂肪乳剂对老年LC患者肝功能和免疫的影响小，值得临床推广。 [关键词]胆囊切除术，腹腔镜；酚类 Effectof Medium-andFatEmulsiononLiver and Propofol Long-chain FunctionImmuneFunc- tionin Patients ZHOU Elderly UndergoingLaparoscopicCholecystectomyFen，YU 300100，(五ina) Jian．_bo(DepartmentofA行Ps咖esioZog了，NankaiHospital，Tianjin observetheeffectof medium-andfatemulsiononliverfunc- [Abstract][()bjective]Topropofol long-chain fionandimmunefunctioninelderlypatients undergoinglaparoscopic ASA dividedinto Aand B 40in IA：were with each． I～Ⅱelderlypatientsundergoingrandomly group group was A inducedandmaintainedanesthesiawith fatemulsion B Group 1％propofollong-chain injection．Group wasinducedandmaintainedanesthesiawith medium-chainfatemulsion propofol injection．ECG。bloodpres．一 sureandblood saturationweremonitored．Theliverfunctionandimmunefunctionin before oxygen patients and1h，24hafter were 24hafter alanine surgerymeasured．．[Results]At aminotransfarase surgery，serum