西吡氯铵与聚维酮碘含漱液对口腔念珠菌感染的疗效及安全性对比.pdfVIP

2015年4月第22卷第4期 窑461 窑 窑论著窑 渊临床研究冤 西吡氯铵与聚维酮碘含漱液对口腔念珠菌感染 的疗效及安全性对比 强海燕 渊嘉应学院医学院附属医院 口腔科袁 广东梅州 514000冤 揖摘要铱 目的 对比研究西吡氯铵与聚维酮碘含漱液治疗口腔念珠菌感染的应用价值遥 方法 将苑源例口腔念珠菌感染患者随 机分为两组各猿苑例遥 观察组给予西吡氯铵含漱液治疗袁 对照组给予聚维酮碘含漱液治疗遥 记录两组患者治疗前后的口腔红斑尧 粘膜萎缩以及疼痛症状评分袁 并对比两组患者的临床疗效和不良反应发生率遥 结果 治疗前袁 两组红斑尧 粘膜萎缩以及口腔疼痛 等症状评分相比差异不显著 渊孕 跃园援园缘冤遥 治疗后袁 两组患者以上指标均显著改善袁 且观察组改善程度优于对照组袁 差异具有统计 学意义 渊孕 约园援园缘冤遥 观察组的总有效率为怨苑援猿豫袁 高于对照组的苑愿援源豫袁 不良反应发生率为圆援苑豫袁 低于对照组的圆员援远豫袁 差异均 具有统计学意义 渊孕 约园援园缘冤遥 结论 西吡氯铵用于治疗口腔念珠菌感染的疗效优于聚维酮碘袁 能有效改善患者口腔症状袁 不良反应 少袁 值得临床推广遥 揖关键词铱 西吡氯铵曰 聚维酮碘曰 口腔念珠菌感染曰 疗效 垣 中图分类号院 砸苑愿员援缘源 文献标识码院 粤 doi:10.3969/j.issn.1674-4659.2015.04.0461 A ComparisonofEffect andSafetyof CetylpyridiniumChlorideandPovidone Iodine onOral Candidiasis QIANGHaiyan (Department ofStomatology, theAffiliated Hospital ofMedical SchoolofJiaying College,Meizhou 514000, China) [Abstract] Objective To compare and study the application value of cetylpyridinium chloride and povidone iodine in the treatment of oral candidiasis. Methods 74 cases of patients with oral candidiasis were randomly divided into two groups, with 37 cases per group. The observation group was given cetylpyridinium chloride gargle, the control group was given povidone iodine gargle. The scores of oral erythroplakia, mucosa atrophy and pain before and after treatment were recorded, the clinical effect and incidence of adverse reactions were compared. Results The scores of oral erythroplakia, mucosa atrophy and pain before treatment had no significant difference (P0.05). After tr