神经病变检查方法比较-英.pdfVIP

Diabetes Research and Clinical Practice 70 (2005) 8–12 /locate/diabres A comparison of the monofilament with other testing modalities for foot ulcer susceptibility B. Miranda-Palma a, J.M. Sosenko a,*, J.H. Bowker b, M.S. Mizel b, A.J.M. Boulton a a Division of Endocrinology, Department of Internal Medicine, Diabetes Research Institute, University of Miami School of Medicine, P.O. Box 016960 (D-110), Miami, FL 33101, USA b Department of Orthopedic Surgery, Diabetes Research Institute, University of Miami School of Medicine, P.O. Box 016960 (D-110), Miami, FL 33101, USA Received 19 November 2004; accepted 18 February 2005 Available online 28 March 2005 Abstract We studied the number of testing sites and the proportion needed to be insensate for the optimal assessment of foot ulcer risk with the 10 g monofilament. Also, we compared the sensitivity and specificity of the 10 g monofilament with other methodologies. Fifty-two individuals with either a current foot ulcer, a history of a foot ulcer or the presence of Charcot neuroarthopathy and 51 individuals with no history of any of these conditions were assessed with the 10 g monofilament at four sites on each foot, the 128 Hz tuning fork at the halluces, the Biothesiometer at the halluces and the modified neuropathy disability score. Sensitivities and specificities were calculated for the various modalities. The Biothesiometer and the neuropathy disability score had the highest sensitivitie