Brownian Dynamics Simulation of Nucleosome Formation and Disruption under Stretching.pdfVIP

Brownian Dynamics Simulation of Nucleosome Formation and Disruption under Stretching ∗ Wei Li, Shuo-Xing Dou, Peng-Ye Wang Laboratory of Soft Ma tter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China Abstract Using a Brownian dynamics simulation, we numerically studied the interaction of DNA with histone and proposed an octamer-rotation model to describe the process of nucleosome formation. Nucleosome dis