MATCH研究原文.pdfVIP

Articles Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial Hans-Christoph Diener, Julien Bogousslavsky, Lawrence M Brass, Claudio Cimminiello, Laszlo Csiba, Markku Kaste, Didier Leys, Lancet 2004; 364: 331–37 Jordi Matias-Guiu, Hans-Jürgen Rupprecht, on behalf of the MATCH investigators* See Comment page 305 *Members listed at end of report Summary Department of Neurology, Background Clopidogrel was superior to aspirin in patients with previous manifestations of atherothrombotic disease in University of Essen, the CAPRIE study and its benefit was amplified in some high-risk subgroups of patients. We aimed to assess whether Hufelandstrasse 55, addition of aspirin to clopidogrel could have a greater benefit than clopidogrel alone in prevention of vascular events 45122 Essen, Germany (Prof H C Diener MD) with potentially higher bleeding risk. Department of Neurology,