《Effect of cytotoxic Tlymphocyte antigen4 TNFalpha polymorphisms on osteosarcoma evidences from a metaanalysis》.pdfVIP
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e F—alpha
antigen一4,TN
frOma
onosteosarcoma:evidences
polymorphisms
Tan93
JianweiLiul,Jan.wr锄矿,WeipingJian91,Yujin
Affiliated of Medical 53003 ofClinical
of Third 1,China;2CenterLaboratory,
1DepartmentOsteology,the HospitalGuangxi University,Nanning
Affiliated of Medical for of of
Nationalities,Baise533000,China;3DepartmentOsteology,AffiliatedHospitalYoujiang
HospitalYoujiang College
Medical for
Nationalities,Baise533000,China
College
ThirdAffiliated Medical Road13,Narming
ofOsteology,theHospitalofGuangxiUniversity,Dancun
Correspondingto:WeipingJiang.Department
53003 liudocnn@163.com.
1,China.Emaih
of
studieshave therole
Objective:Previous cytotoxicT-lymphocyteantigen一4(CTLA-4)and
investigated
tumornecrosis of tIleirresultswereinconsistent.
osteosarcoma,but
factor-alpha仃’NF一∞incarcinogenesis
W.eaimedto t11eassociationsbetweenCTLA一4.TNF—a andosteosarcomarisk
clarify polymorphism by
usingmeta—analysis.
Methods:Wesearchedrelevantstudieswithout restrictionin
language PubMed,EMbase,Cochrane
Scholar National conference
databases,Chinese
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